Met CLIA Kit for Mouse(Mus musculus) | EIAab.comMet CLIA Kit for Mouse(Mus musculus)

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Met (Gene name),

Hepatocyte growth factor receptor (Protein name ), MET_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Met;

Protein name:

Hepatocyte growth factor receptor(HGF receptor);

Alternative:

Proto-oncogene c-Met;HGF/SF receptor;Tyrosine-protein kinase Met;Scatter factor receptor(SF receptor);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer formed of an alpha chain (50 kDa) and a beta chain (145 kDa) which are disulfide linked (By similarity). Binds PLXNB1 and GRB2 (By similarity). When phosphorylated at Tyr-1354, interacts with INPPL1/SHIP2 (By similarity). Interacts with RANBP9 and RANBP10 (By similarity). Interacts with INPP5D/SHIP1. Interacts with SPSB1, SPSB2, SPSB4 and probably SPSB3. SPSB1 binding occurs in the presence and in the absence of HGF, however HGF treatment has a positive effect on this interaction. Interacts with MUC20; prevents interaction with GRB2 and suppresses hepatocyte growth factor-induced cell proliferation. Interacts with GRB10.

Function:

Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

1379

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

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950:

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1050:

1100:

1150:

1200:

1250:

1300:

1350:

1379:

NATYVNVKCV | APYPSLLPSQ | DNIDGEGNT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.86844

Pfam:

PF07714

SMR:

P16056

String:

P16056

Uniprot:

P16056

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ELISA Kit for Mouse HGF receptor

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ELISA Kit for Mouse HGF receptor

Cat.:

E9559m

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96T

ELISA Kit for Mouse HGF receptor

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E9559r

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96T

ELISA Kit for Mouse HGF receptor

Cat.:

E9559h

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ELISA Kit for Mouse HGF receptor

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ELISA Kit for Mouse HGF receptor

Cat.:

E9559p

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96T

ELISA Kit for Mouse HGF receptor

Cat.:

E9559b

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96T

CLIA Kit for Mouse HGF receptor

Cat.:

U9559m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse HGF receptor

Cat.:

U9559b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse HGF receptor

Cat.:

U9559h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse HGF receptor

Cat.:

U9559r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse HGF receptor

Cat.:

U9559p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse HGF receptor

MSDS:

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CLIA Kit for Mouse HGF receptor

MSDS:

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Polyclonal Antibody for Mouse HGF receptor

Cat.:

P9559Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse HGF receptor

Cat.:

P9559Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse HGF receptor

Monoclonal Antibody for Mouse HGF receptor

Protein for Mouse HGF receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Characterization of the mouse met proto-oncogene."
Chan A.M.-L. , King H.W.S. , Deakin E.A. , Tempest P.R. , Hilkens J. , Kroezen V. , Edwards D.R. , Wills A.J. , Brookes P. , Cooper C.S.
Oncogene2:593-599(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family."
Wilks A.F. , Kurban R.R. , Hovens C.M. , Ralph S.J.
Gene85:67-74(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1199-1270
3.

"The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells."
Weidner K.M. , Sachs M. , Birchmeier W.
J. Cell Biol.121:145-154(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 924-935
4.

"Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud."
Bladt F. , Riethmacher D. , Isenmann S. , Aguzzi A. , Birchmeier C.
Nature376:768-771(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEVELOPMENT
5.

"The SH2-containing inositol 5-phosphatase (SHIP)-1 is implicated in the control of cell-cell junction and induces dissociation and dispersion of MDCK cells."
Mancini A. , Koch A. , Wilms R. , Tamura T.
Oncogene21:1477-1484(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH INPP5D
6.

"MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met."
Higuchi T. , Orita T. , Katsuya K. , Yamasaki Y. , Akiyama K. , Li H. , Yamamoto T. , Saito Y. , Nakamura M.
Mol. Cell. Biol.24:7456-7468(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MUC20
7.

"The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues."
Masters S.L. , Yao S. , Willson T.A. , Zhang J.-G. , Palmer K.R. , Smith B.J. , Babon J.J. , Nicola N.A. , Norton R.S. , Nicholson S.E.
Nat. Struct. Mol. Biol.13:77-84(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SPSB1; SPSB2 AND SPSB4

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